Editorial: L-Dopa and Favism

L-Dopa and Behavior

to include the "why" of procedures, but rather presents step-by-step instructions and recipes for the bench technologist. The first of the three sections deals with biochemical identification tests, from acetate utilization to Voges-Proskauer. Each includes descriptions of purpose, principle, mechanisms, equipment and reagents, method, and interpretation. The format is short, lucid, and informa...

L-dopa

Oleh Hornykiewicz was born in 1926 in Sykhiw, Poland (now Ukraine). In 1951, he received his M.D. degree from the University of Vienna and joined the faculty of his alma mater the same year and has worked there ever since. He also served for twenty years as chairman of the Institute of Biochemical Pharmacology. In 1967, he began a long association with the University of Toronto in Canada and, i...

Favism.

Hypotension caused by L-dopa.

In 20 patients with idiopathic Parkinsonism maximum tolerated doses of L-dopa were found to induce a mean reduction in blood pressure (erect systolic) of 19.3 mm.Hg, without any significant change in pulse rate. This hypotension may be due to dopamine, acting on adrenergic nerve endings or on the central nervous system itself.

Parkinson disease , L - dopa , and neuropathy

Neurology 2011;77:1938–1939 Is it conceivable that for 40 years we have overlooked an insidious long-term levodopa treatment adverse effect, such as neuropathy, in idiopathic Parkinson disease (IPD)? In this issue of Neurology, Rajabally and Martey1 take up the already controversial question, recently mooted by Toth et al.,2 of the increased prevalence of neuropathy in chronic levodopatreated I...